Parkinson s Disease A Progressive Neurodegenerative...

Introduction The research problem Parkinson’s Disease (PD) is a progressive neurodegenerative movement disease affecting approximately 1% of people at age 60. It is the most second most commonly occurring neurodegenerative disease in the elderly (after Alzheimer’s Disease). In PD patients, loss of dopamine-producing neurons results in a range of motor and non-motor symptoms. The prevalence of PD increases with age, and currently there is no cure, no means of slowing the disease progression, and no means of prevention. Unfortunately there is currently no objective, quantifiable diagnostic test for PD – diagnosis relies on observation of a combination of visible symptoms by a specialist (typically a neurologist) and there is a high rate of misdiagnosis. Just as importantly, a patient may have the disease for many years before it is diagnosed. By the time of diagnosis, typically 60% or more of the neurons in the affected part of the brain (the substantia nigra) have already been lost. There is active research into the causes of PD and it is likely that both neuroprotective drugs and treatments to slow the disease progression will be developed. However, the efficacy of such treatments depends on early diagnosis, before the irreversible loss of dopaminergic neurons has occurred. Significance of the research The basic premise of the research is that PD, being a disease that affects movement, will cause changes in the characteristics of hand and finger movement and that some ofShow MoreRelatedThe Purpose Of My Research Conducted For This Paper Was1677 Words   |  7 Pagesmy research conducted for this paper was to examine the relationship between Parkinson s disorder and its connection to the anatomy of the human body. Parkinson s is a progressive disorder of the nervous system that affects movement due to the loss of Dopamine. Dopamine which is a neurotransmitter located in the brain allows signals to be transported from one nerve cell to another. Its purpose is to regulate both movement and cognition. The loss of these chemical messengers can cause both stiffnessRead MoreSymptoms And Symptoms Of Parkinson s Disease Essay831 Words   |  4 PagesParkinson Disease by Melissa Green Topical Bibliography In partial fulfillment of the writing requirement for Anatomy and Physiology 304 and the Department of Speech-Language Pathology SUNY Buffalo State Fall 2016 Parkinson’s disease is a neurodegenerative disorder characterized by motor symptoms or tremors, rigidity, (bradykinesia) or slowness of movement and posture instability. Parkinson’s involves the malfunction and death of vital nerve cells in theRead MoreIs Parkinson Disease A Disease?1290 Words   |  6 Pages Parkinson Disease Danielle West University Of Arkansas Fort Smith Medical Terminology Fall of 2015 Introduction Parkinson is a disease that is a glitch in the neurons in the brain, which frequently affects the substantia nigra. Part of the dying neurons produces a chemical called dopamine. As this progresses, the dopamine in the brain decreases. Dopamine is a chemical in the brain which helps the body regulate coordination and movement in the body. Once Parkinson Disease (PD)Read MoreAlzheimer s Disease And Its Effects On The Lives Of Millions Americans Essay1714 Words   |  7 Pages â€Æ' Introduction Neurodegenerative diseases continue to affect the lives of millions Americans each year, with incidence and prevalence rates ever increasing. These diseases cause degeneration or death of nerve cells in the brain. These diseases can cause a financial and emotional burden on not only patients themselves, but also family members and care givers as well. Molecular mechanisms that underlie these diseases have remained relatively unclear, despite much research. 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Whether it is albinism or red hair (also referred to as day walkers or ginger) height or heath both parent carry the autosomal trait that is passed to the child. An autosomal recessive disorder means that two copies of an abnormal gene must be present in order for the disease or trait to develop. A mutation in a gene on one of the first 22 non-sex chromosomes canRead MoreThe Disease Of Parkinson s Disease1648 Words   |  7 Pages Abstract Parkinson’s disease has been cataloged as one of the most serious and slowly progressive neurodegenerative disease that affects a wide array of motor and non-motor aspects that impact the function of a person. Afflicting over four million Americans and the second most common neurological disorder after Alzheimer’s disease, Parkinson’s continues to take its toll on the neurological health of many(Constantinescu et al, 2007 ). James Parkinson, a British physician first coinedRead MoreParkinsons Disease and Small Farming Community Essay771 Words   |  4 PagesCase Study Parkinson’s Disease Scenario L.C. is a 78-year-old white man with a 4-year history of Parkinson’s disease (PD). He is a retired engineer, is married, and lives with his wife in a small farming community. He has 4 adult children who live close by. He is taking carbidopa-levodopa, pergolide, and amantadine. L.C. reports that overall he is doing â€Å"about the same† as he was at his last clinic visit 6 months ago. He reports that his tremor is about the same, his gait is perhaps a little moreRead MoreThe Parkinson s Disease ( Pd )1058 Words   |  5 PagesIntroduction The Parkinson s disease (PD) is the second most common neurodegenerative disorder after Alzheimer s disease (Lang and Lozano, 1998). It affects about 1% of the population with different ethnic backgrounds throughout the world over the age of 65 (Tanner and Goldman, 1996). The aetiology of Parkinson s disease is not well understood; however, genetic and environmental factors are thought to play a role (Checkoway and Nelson, 1999). Pathologically, PD is characterised by mitochondrialRead MoreNot Only Is It Detrimental To The Social Development Of1604 Words   |  7 Pagesthat, â€Å"Many of these lifestyle changes have been shown to lower the risk of other diseases, like heart disease and diabetes, which have been linked to Alzheimer s† (Alzheimer s Association Organization). Even if evidence cannot definitively determine if these lifestyle changes directly relate to a prolonged life, there are correlations that have been developed in a multitude of studies. In terms of Parkins on’s disease, it has been proven time and time again that the slowing of motor function can be